HCSL Software Repository
DiagAccU
Chatzimichail RA, Chatzimichail T, Hatjimihail AT. DiagAccU: A Software Program for the Uncertainty Estimation of Diagnostic Accuracy Measures Under Parametric Distributions. Ver. 1.0.0. Hellenic Complex Systems Laboratory; 2025.
Software Synopsis
DiagAccU implements a threshold-based computational framework to quantify measurement, sampling, and combined uncertainty for sixteen diagnostic accuracy in screening and diagnostic testing. Measurement uncertainty is modelled with linear and nonlinear heteroscedastic functions. Uncertainty is propagated using first-order Taylor-series expansion, and effective degrees of freedom and expanded uncertainty is estimated via the Welch–Satterthwaite formula. Optimality conditions are derived numerically where where interior optima exist. The program supports selection of clinically meaningful thresholds (confirmation vs exclusion), transparent uncertainty reporting, and sensitivity analyses under alternative distributional assumptions. It provides parameter entry, batch computation, and publication-grade plots for reporting and study design.
Software Requirements
Operating systems: Microsoft Windows, Linux, Apple macOS and iOS
Programming language: Wolfram Language
Source file format: Wolfram Notebook
Other software requirements: Wolfram Player (freely available) or Wolfram Mathematica
Recommended system: Intel Core i9 or equivalent CPU and 32GB+ of RAM
Terms of Use
The material made freely available by Hellenic Complex Systems Laboratory is subjec to its Terms of Use.