HCSL Software Repository

Diagnostic Uncertainty

Chatzimichail T, Hatjimihail AT. Diagnostic Uncertainty: A Software Tool for Calculating the Uncertainty of Diagnostic Accuracy Measures. Ver. 1.1.0. Drama: Hellenic Complex Systems Laboratory, 2021


This is a software tool for calculating the uncertainty of diagnostic accuracy measures, as diagnostic accuracy is fundamental to clinical decision making. It provides six modules with nine submodules for calculating and plotting the standard measurement, sampling and combined uncertainty and the resultant confidence intervals of various diagnostic accuracy measures of screening or diagnostic tests, which measure a normally distributed measurand, applied at a single point in time in samples of non-diseased and diseased populations. This is done for differing sample sizes, mean and standard deviation of the measurand, diagnostic threshold and standard measurement uncertainty of the test.

Source code (Revised on 06/12/2023)


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Software Requirements

Operating Systems: Microsoft Windows, Linux, Apple iOS

Programming language: Wolfram Language

Software source code file format: Wolfram Notebook

Other software requirements: Wolfram Player (freely available) or Wolfram Mathematica

Recommended system: Intel Core i9 or equivalent CPU and 32GB+ of RAM

Software license: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License