HCSL Software Repository


Chatzimichail T, Hatjimihail AT. Relation: A Software Tool for Exploring the Relation between Diagnostic Accuracy and Measurement Uncertainty. Ver. 1.0.1. Drama: Hellenic Complex Systems Laboratory, 2020


This is an exploratory software tool for the relation between diagnostic accuracy measures and measurement uncertainty, as diagnostic accuracy is fundamental to clinical decision making, while measurement uncertainty is critical to quality and risk management in laboratory medicine. It provides five modules with six submodules for calculating, optimizing, plotting and comparing various diagnostic accuracy measures and the corresponding risk of diagnostic or screening tests measuring a normally distributed measurand, applied at a single point in time in non-diseased and diseased populations. This is done for differing prevalence of the disease, mean and standard deviation of the measurand, diagnostic threshold, standard measurement uncertainty of the tests and expected loss.

Source code


Software Requirements

Operating Systems: Microsoft Windows, Linux, Apple iOS

Programming language: Wolfram Language

Software source code file format: Wolfram Notebook

Other software requirements: Wolfram Player (freely available) or Wolfram Mathematica

Recommended system: Intel Core i7 or equivalent CPU and 16GB+ of RAM

Software license: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License